Fonda D, Woodward M, D'Astoli M, Chin W F
Department of Geriatric Medicine, Caulfield General Medical Centre, Victoria, Australia.
Age Ageing. 1995 Jul;24(4):283-6. doi: 10.1093/ageing/24.4.283.
We aimed to study the impact of conservative non-pharmacological, non-surgical management on quality of life in elderly incontinent patients. Community-dwelling patients age 60 years or older were randomized to receive immediate or delayed conservative management. A number of questions relating to quality of life were administered at admission and then at 2, 4, 8 and 12 months. By 4 months, incontinence was cured in 25% and improved in 63% of patients. The frequency and severity of incontinence was reduced (p < 0.001), and deferment time was improved (p < 0.01). There were statistically significant improvements in subjective quality of life measures at 4 and 12 months involving depression (p < 0.001), isolation (p < 0.03), embarrassment (p < 0.001), laundry (p < 0.001) and smell (p < 0.02) when comparing these variables with initial assessment. This effect did not appear to be a placebo effect as evidenced by comparison with the delayed intervention group, and was sustained over 12 months. There are significant short- and long-term benefits to the quality of life of older patients with incontinence when treated by conservative measures. Intervention studies should measure and report quality of life as an outcome variable.
我们旨在研究保守的非药物、非手术治疗对老年失禁患者生活质量的影响。将60岁及以上的社区居住患者随机分为立即接受或延迟接受保守治疗两组。在入院时以及之后的2个月、4个月、8个月和12个月，对一系列与生活质量相关的问题进行询问。到4个月时，25%的患者失禁得到治愈，63%的患者病情有所改善。失禁的频率和严重程度降低（p<0.001），延迟时间缩短（p<0.01）。与初始评估相比，在4个月和12个月时，主观生活质量指标在抑郁（p<0.001）、社交隔离（p<0.03）、尴尬（p<0.001）、洗衣问题（p<0.001）和气味问题（p<0.02）方面有统计学意义的改善。与延迟干预组相比，这一效果似乎并非安慰剂效应，且在12个月内持续存在。采用保守措施治疗老年失禁患者对其生活质量有显著的短期和长期益处。干预研究应将生活质量作为一个结果变量进行测量和报告。
