Seress L
J Hirnforsch. 1978;19(5):395-403.
The effect of daily triiodothyronine (T3) treatment (first injection on the day of birth) was studied on the postnatal development of various parts of the rat brain. It was found that the T3 treatment resulted in an increase of the cell multiplication in the external grannular layer of the cerebellum but decreased the cell division or had no significant effect in the periventricular germinal layer and in the polymorph layer of the dentate gyrus. From the 10th day the T3 treatment resulted in a decrease of the cell division in all secondary germinal layers examined. As a reason for this different effect is can be suggested that the triidothyronine acts differently upon the various neuronal and glial precursors or upon the germinal layers producing them.
研究了每日注射三碘甲状腺原氨酸（T3）（出生当天首次注射）对大鼠大脑各部分产后发育的影响。结果发现，T3治疗导致小脑外颗粒层细胞增殖增加，但在脑室周围生发层和齿状回多形层中细胞分裂减少或无显著影响。从第10天起，T3治疗导致所有检查的次级生发层中细胞分裂减少。造成这种不同影响的原因可能是，三碘甲状腺原氨酸对各种神经元和神经胶质前体细胞或产生它们的生发层的作用不同。
