Schweitzer M E, Fort J
Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.
AJR Am J Roentgenol. 1995 Dec;165(6):1469-71. doi: 10.2214/ajr.165.6.7484589.
Polymyositis is an inflammatory disorder of muscle that is often difficult to diagnose. The purpose of this study was to assess the usefulness and cost-effectiveness of MR imaging as a biopsy guide in patients with suspected polymyositis as an alternative to a blind biopsy.
Our subjects were 25 patients with clinically suspected and ultimately confirmed polymyositis, 14 of whom had preoperative MR imaging at 1.5 T (including axial T1-weighted, axial T2-weighted [fat saturated], coronal T1-weighted, and coronal fast short-T1 inversion recovery images of both entire extremities). Images were prospectively interpreted for a specific location for a biopsy that showed the most muscle edema with the least atrophy. Surgical results and the estimated true cost of medical care (cost-accounting method) were compared between patients with preoperative MR images and patients whose biopsy site was selected on the basis of clinical criteria.
Among the 14 patients whose biopsy site was selected on the basis of MR findings, only one biopsy result was false-negative. Patients without imaging had five biopsies with false-negative results. Patients with preoperative MR images averaged actual medical costs of $14,000 compared with $20,000 for those without MR images. Hospitalization time averaged 12 days for patients with MR images for guidance compared with 14 days for those without MR images. The average daily cost was $1,150 for the patients with MR images compared with $1,390 for those without.
We conclude that MR imaging not only can aid in surgical planning but also can decrease the costs of patient care for patients with suspected polymyositis.
多发性肌炎是一种肌肉炎症性疾病,常常难以诊断。本研究的目的是评估磁共振成像(MR成像)作为疑似多发性肌炎患者活检引导手段的有效性和成本效益,以替代盲目活检。
我们的研究对象为25例临床疑似且最终确诊为多发性肌炎的患者,其中14例在术前接受了1.5T的MR成像检查(包括双侧整个肢体的轴位T1加权像、轴位T2加权像[脂肪抑制]、冠状位T1加权像以及冠状位快速短T1反转恢复序列图像)。对图像进行前瞻性解读,以确定活检的特定部位,该部位显示肌肉水肿最明显且萎缩最少。比较术前有MR图像的患者与根据临床标准选择活检部位的患者的手术结果及医疗护理的估计实际成本(成本核算方法)。
在根据MR检查结果选择活检部位的14例患者中,只有1例活检结果为假阴性。未进行成像检查的患者中有5例活检结果为假阴性。术前有MR图像的患者平均实际医疗费用为14,000美元,而没有MR图像的患者为20,000美元。有MR图像引导的患者平均住院时间为12天,而没有MR图像的患者为14天。有MR图像的患者平均每日费用为1,150美元,而没有MR图像的患者为1,390美元。
我们得出结论,MR成像不仅有助于手术规划,还能降低疑似多发性肌炎患者的医疗护理成本。