Cody R J
Cardiology Division, Ohio State University Medical Center, Columbus 43210, USA.
Am Fam Physician. 1995 Nov 1;52(6):1801-6.
Myocardial infarction and congestive heart failure are associated with high morbidity and mortality rates. The results of recent clinical trials support a beneficial role for angiotensin-converting enzyme (ACE) inhibitors in attenuating mortality from myocardial infarction and left ventricular dysfunction. Large-scale survival studies provide practical evidence that the addition of an ACE inhibitor to conventional therapy with diuretics and digoxin can significantly reduce the number of hospital admissions and the risk of death related to progressive heart failure.
心肌梗死和充血性心力衰竭的发病率和死亡率都很高。近期临床试验结果表明，血管紧张素转换酶（ACE）抑制剂在降低心肌梗死死亡率和左心室功能障碍方面具有有益作用。大规模生存研究提供了切实证据，即在常规使用利尿剂和地高辛治疗的基础上加用ACE抑制剂，可显著减少住院次数以及与进行性心力衰竭相关的死亡风险。
