Ekesten B, Torrång I
Department of Medicine, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Am J Vet Res. 1995 Sep;56(9):1138-43.
Ocular examination, including gonioscopy and ultrasonographic biometry (biological measurement), was performed in healthy, purebred Samoyeds. When the dogs were subclassified according to the degree of kinship with cases of primary angle-closure glaucoma, it was found that the opening of the ciliary cleft was wider in dogs less related to dogs with primary angle-closure glaucoma than in more closely related dogs. Furthermore, multivariate analysis of the material indicated that parentage of a dog has a substantial effect on the intraocular distances studied in this investigation (relative depth of the opening of the ciliary cleft, relative corneal thickness, relative anterior chamber depth, relative lens thickness, and relative length of the vitreous body). Finally, heritability of the relative depth of the opening of the ciliary cleft was estimated at 56% and that of the common environmental factor at 19%. The results are indicative of a hereditary component in primary angle-closure glaucoma in the Samoyed breed.
对健康的纯种萨摩耶犬进行了眼科检查，包括前房角镜检查和超声生物测量（生物学测量）。当根据与原发性闭角型青光眼病例的亲缘程度对犬进行亚分类时，发现与原发性闭角型青光眼犬亲缘关系较远的犬的睫状沟开口比亲缘关系较近的犬更宽。此外，对该材料的多变量分析表明，犬的亲本对本研究中所研究的眼内距离（睫状沟开口的相对深度、相对角膜厚度、相对前房深度、相对晶状体厚度和玻璃体相对长度）有实质性影响。最后，睫状沟开口相对深度的遗传率估计为56%，共同环境因素的遗传率为19%。结果表明萨摩耶犬种原发性闭角型青光眼存在遗传成分。
