Burgos Revilla F J, Orofino Ascunce L, Mayayo Dehesa T, Marcen Letosa R, Orte Martínez L, Ortuño Mirete J, Escudero Barrilero A
Servicio de Urología, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Madrid, España.
Arch Esp Urol. 1995 Sep;48(7):701-7.
The incidence of arterial hypertension post-renal transplantation has been reported to be 48.6%. The present study investigated the usefulness of echo Doppler in detecting renal artery stenosis and the effects of arterial pressure control and hypotensive agents on the vascular resistance of the renal graft.
A total of 234 echo Doppler studies were done in 110 patients. The pulsatility index (PI), resistance index (RI), acceleration and mean velocity (MV), maximum systolic (SVMX) and minimum diastolic (DVMN) velocities of the external iliac, renal, segmental, interlobar and arcuate arteries were determined.
In the stenotic segment, an elevation of SVMX was observed, followed by turbulent flow in the post-stenotic segment in 73% of the cases with arterial stenosis. The hypertensive patients had a higher external iliac artery RI than the normotensives. The beta-blockers reduced the RI in large vessels (external iliac), the vasodilators in medium-sized extraparenchymal vessels (segmental) and the calcium antagonists changed the PI in the smaller caliber intraparenchymal vessels (interlobar and arcuate).
Evaluation by echo Doppler is the first diagnostic approach in patients suspected as having arterial stenosis of the renal graft. It permits evaluating blood flow changes from hypertension and hypotensive agents.
据报道,肾移植术后动脉高血压的发生率为48.6%。本研究调查了超声多普勒在检测肾动脉狭窄中的作用,以及动脉压控制和降压药物对移植肾血管阻力的影响。
对110例患者进行了总共234次超声多普勒检查。测定了髂外动脉、肾动脉、节段动脉、叶间动脉和弓状动脉的搏动指数(PI)、阻力指数(RI)、加速度和平均速度(MV)、最大收缩速度(SVMX)和最小舒张速度(DVMN)。
在狭窄段,73%的动脉狭窄病例中观察到SVMX升高,随后狭窄后段出现湍流。高血压患者的髂外动脉RI高于血压正常者。β受体阻滞剂降低了大血管(髂外动脉)的RI,血管扩张剂降低了中等大小的实质外血管(节段动脉)的RI,钙拮抗剂改变了较小口径的实质内血管(叶间动脉和弓状动脉)的PI。
超声多普勒评估是怀疑有移植肾动脉狭窄患者的首要诊断方法。它可以评估高血压和降压药物引起的血流变化。