[去甲肾上腺素和多巴胺激动剂及拮抗剂对某些昆虫和甲壳类动物耗氧量的影响]
[The effect of noradrenaline and dopamine agonists and antagonists on oxygen consumption in some insect and crustacean species].
作者信息
Weischer M L, Hano R
机构信息
Institut für Pharmakologie und Toxikologie, Westfälischen Wilhelms-Universität Münster.
出版信息
Arzneimittelforschung. 1995 Sep;45(9):1032-5.
The effect of drugs on oxygen consumption in some invertebrate species (insect larvae and crustacea) was investigated. Insect larvae showed an increase in oxygen consumption under the influence of sympathomimetic drugs such as isoprenaline or orciprenaline which could be prevented by beta-receptor antagonists like propranolol or butoxamine. The drugs had no effect in crustacea. On the other hand, in these animals dopamine agonists of different chemical structure (amphetamine, apomorphine, lisuride) caused an increase in oxygen consumption whereas the dopamine antagonist metoclopramide had an opposite effect.
研究了药物对一些无脊椎动物物种（昆虫幼虫和甲壳类动物）耗氧量的影响。在拟交感神经药物如异丙肾上腺素或奥西那林的影响下，昆虫幼虫的耗氧量增加，而普萘洛尔或布托沙明等β受体拮抗剂可阻止这种增加。这些药物对甲壳类动物没有影响。另一方面，在这些动物中，不同化学结构的多巴胺激动剂（苯丙胺、阿扑吗啡、利苏瑞）会导致耗氧量增加，而多巴胺拮抗剂甲氧氯普胺则有相反的作用。
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