Mendoza Espejo R, Díaz Pérez de Madrid J, Buitrago F
Centro de Salud Universitario La Paz, Unidad Docente de Medicina de Familia y Comunitaria, Badajoz.
Aten Primaria. 1995 Oct 15;16(6):364-6.
To compare the effectiveness of two interventions in the treatment of obese patients: hypocaloric diet and hypocaloric diet plus serotoninergic medication.
Randomised clinical trial.
Primary Care. Out-patient Endocrinology clinic.
The trial included 60 obese adults, assigned at random to two groups of 30 each. Both groups were comparable for sex, age, weight and Body Mass Index. Weight controls were performed at 2, 4 and 6 months.
There were no significant differences in weight losses at the times studied (2, 4 and 6 months) between the Control (Hypocaloric diet) and Study (Hypocaloric diet plus medication) groups. There were significant weight losses in both groups analysed between 2 and 4 months, with a Body Mass Index which went down from 36.2 to 34.12 and from 35.52 to 33.57 (p < 0.001) in the Control and Study groups, respectively.
No significant differences were observed in the results obtained for obese patients between a hypocaloric diet supplemented by serotoninergic medication and a hypocaloric diet.
比较两种干预措施治疗肥胖患者的效果：低热量饮食和低热量饮食加血清素能药物。
随机临床试验。
初级保健。门诊内分泌诊所。
该试验纳入60名肥胖成年人，随机分为两组，每组30人。两组在性别、年龄、体重和体重指数方面具有可比性。在2、4和6个月时进行体重控制。
在研究的时间点（2、4和6个月），对照组（低热量饮食）和研究组（低热量饮食加药物）之间的体重减轻没有显著差异。两组在2至4个月期间均有显著体重减轻，对照组和研究组的体重指数分别从36.2降至34.12和从35.52降至33.57（p<0.001）。
在肥胖患者中，补充血清素能药物的低热量饮食和低热量饮食在获得的结果上没有观察到显著差异。
