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[居住在不同放射性污染水平地区的供体淋巴细胞适应性反应的细胞遗传学分析]

[The cytogenetic analysis of the adaptive response in the lymphocytes of donors living in areas with different levels of radioactive contamination].

作者信息

Riabchenko N I, Antoshchina M M, Nasonova V A, Fesenko E V

出版信息

Radiats Biol Radioecol. 1995 Sep-Oct;35(5):670-5.

PMID:7489101
Abstract

The adaptive response was studied in peripheral lymphocytes of healthy donors residing at territories with various levels of radioactive contamination. For donors from a clean territory (the town of Obninsk), the adaptive response depended on the cell cycle stage at which lymphocytes had been exposed to adaptive and challenge doses. The most expressed adaptive response was observed if lymphocytes had been exposed to the adaptive dose 0.05 Gy at G0 or G1 stage and to the challenge dose 0.5 Gy at G2 stage. Lymphocytes of donors from a contaminated territory (the town of Novozybkov) did not show an adaptive response in the conditions described above.

摘要

对居住在不同放射性污染水平地区的健康供体的外周淋巴细胞中的适应性反应进行了研究。对于来自清洁地区(奥布宁斯克市)的供体,适应性反应取决于淋巴细胞接受适应性剂量和激发剂量时所处的细胞周期阶段。如果淋巴细胞在G0或G1期接受0.05 Gy的适应性剂量,并在G2期接受0.5 Gy的激发剂量,则观察到最明显的适应性反应。来自污染地区(新兹布科夫市)的供体的淋巴细胞在上述条件下未表现出适应性反应。

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