Cittadini G, Murolo C, Scarpati D
Radiol Med. 1978 Sep;64(9):1021-38.
The role of what has come to be called "the four R's" of modern radiobiology is reviewed from a general and applied point of view. Especially, repair of subletal damage, redistribution of cells within their cycle, tissue repopulation, cell reoxygenation, are considered with attention to their intervention in the sterilization of tumor clonogenic cells in human radiotherapy.
从一般和应用的角度对现代放射生物学中所谓的“四个R”的作用进行了综述。特别是，对亚致死损伤的修复、细胞在其周期内的再分布、组织再增殖、细胞再氧合进行了探讨，关注它们在人类放射治疗中对肿瘤克隆源性细胞的杀灭作用的干预。
