LiPuma J J, Stull T L
Medical College of Pennsylvania, Philadelphia, USA.
Infect Dis Clin North Am. 1995 Sep;9(3):561-74.
The utility of various antibacterial agents for therapy of infectious diseases in children is determined by the unique pharmacokinetics and potential toxicity in children. The important age-related principle of pharmacokinetics is reviewed in the first section of this article; the second section focuses on specific therapeutic agents and their use in children. Particular emphasis is given to the use of new antibiotics in children, including the new oral cephalosporins and macrolides.
各种抗菌药物用于治疗儿童感染性疾病的效用取决于儿童独特的药代动力学和潜在毒性。本文第一部分回顾了药代动力学中与年龄相关的重要原则；第二部分重点介绍了特定的治疗药物及其在儿童中的应用。特别强调了新抗生素在儿童中的使用，包括新型口服头孢菌素和大环内酯类药物。
