Siar C H, Ng K H
Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya, Malaysia.
J Nihon Univ Sch Dent. 1995 Sep;37(3):163-9. doi: 10.2334/josnusd1959.37.163.
The lining epithelium of 15 cases of odontogenic keratocyst (OKC) was evaluated immunohistochemically. The peroxidase-antiperoxidase technique was applied to study the distribution of polyclonal keratin and S-100 protein while the indirect method was used to examine monoclonal vimentin and desmin reactivity. Consistent positive keratin staining was revealed in the lining epithelium of all 15 OKCs with additional intense staining in the stratum corneum. None of the cases showed vimentin or desmin reactivity within the lining epithelium elements. One of the 15 cysts studied showed positive S-100 protein staining in the nuclei of the lining epithelial cells. The pertinent literature on the immunophenotyping of the lining epithelium of OKC is reviewed.
对15例牙源性角化囊肿（OKC）的衬里上皮进行了免疫组织化学评估。采用过氧化物酶-抗过氧化物酶技术研究多克隆角蛋白和S-100蛋白的分布，同时采用间接法检测单克隆波形蛋白和结蛋白的反应性。在所有15例OKC的衬里上皮中均显示出一致的角蛋白阳性染色，角质层有额外的强染色。所有病例的衬里上皮成分均未显示波形蛋白或结蛋白反应性。在研究的15个囊肿中，有1个囊肿的衬里上皮细胞核显示S-100蛋白阳性染色。本文回顾了有关OKC衬里上皮免疫表型的相关文献。
