Lewin J, Lewis S
University Department of Psychiatry, Royal Free Hospital School of Medicine, London, U.K.
J Psychosom Res. 1995 Jul;39(5):531-48. doi: 10.1016/0022-3999(94)00026-3.
Duodenal ulcer (DU) is a common medical disorder which frequently becomes chronic. The factors involved in the aetiology of DU are poorly understood. Evidence for the contribution of psychosocial factors to the onset of DU is reviewed in the context of evidence of organic factors, genetic and environmental, with special reference to new evidence of infectious agents in the aetiology of DU. Recent progress in understanding of biological forces of duodenal ulcer disease has lead to a substantially revised view of psychosomatic factors. Although these may be of significance, their relative contribution to aetiology is likely to be modest.
十二指肠溃疡（DU）是一种常见的内科疾病，常转为慢性。目前对DU病因所涉及的因素了解甚少。本文结合有机因素、遗传和环境因素的证据，特别是关于DU病因中感染因子的新证据，综述了社会心理因素对DU发病作用的证据。对十二指肠溃疡病生物学因素认识的最新进展，使人们对心身因素的看法有了很大改变。虽然这些因素可能有一定意义，但它们在病因学中的相对作用可能不大。
