以色列人群中乙型肝炎表面抗原的变体

wVariants of the hepatitis B surface antigen in Israeli populations.

作者信息

Sandler S G, Couroucé A M, Soulier J P

出版信息

Vox Sang. 1978;34(3):149-51. doi: 10.1111/j.1423-0410.1978.tb02457.x.

DOI:10.1111/j.1423-0410.1978.tb02457.x

Abstract

A survey of w variants of the hepatitis B surface antigen (HBsAg) among native and immigrant Israelis revealed that the subtype ayw2 predominated among asymtpomatic HBsAg carriers (69%), and patients with acute (83%) and chronic active hepatitis B (81%). The subtypes ayw3, ayw4 and adw2, uncommon in native populations, were detected in carriage by immigrants and transients. Nevertheless, the high prevalence of ayw2 among native Israeli carriers (87%), and in particular natives with acute 93%) and chronic active hepatitis B (86%), indicates that the introduction of nonindigenous viral strains has not overtly altered the anticipated geographic distribution of hepatitis B viruses.

摘要

对以色列本地人和移民中的乙肝表面抗原（HBsAg）w 变体进行的一项调查显示，ayw2 亚型在无症状 HBsAg 携带者中占主导地位（69%），在急性乙肝患者（83%）和慢性活动性乙肝患者（81%）中也占主导地位。ayw3、ayw4 和 adw2 亚型在本地人群中不常见，在移民和流动人口的携带者中被检测到。然而，ayw2 在以色列本地携带者中（87%），尤其是患有急性乙肝（93%）和慢性活动性乙肝（86%）的本地人中高度流行，这表明非本土病毒株的引入并未明显改变乙肝病毒预期的地理分布。