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阴茎海绵体内注射前列腺素E1治疗所致阴茎瘢痕形成:危险因素分析

Penile scarring with intracavernous injection therapy using prostaglandin E1: a risk factor analysis.

作者信息

Chen R N, Lakin M M, Montague D K, Ausmundson S

机构信息

Department of Urology, Cleveland Clinic Foundation, Ohio, USA.

出版信息

J Urol. 1996 Jan;155(1):138-40.

PMID:7490812
Abstract

PURPOSE

We attempted to identify risk factors for penile scarring in patients using prostaglandin E1 injection therapy.

MATERIALS AND METHODS

Records of 92 patients using prostaglandin E1 therapeutically were reviewed. With statistical methods, patients with (15) and without (77) scarring were compared.

RESULTS

No significant differences between the 2 groups were found regarding duration of followup, injection frequency, prostaglandin E1 dose per injection, total number of injections or total prostaglandin E1 dose. Patients with initial penile scarring did not have a significantly higher incidence of further scarring with prostaglandin E1.

CONCLUSIONS

Penile scarring with prostaglandin E1 injection therapy is sporadic and unpredictable. Patients with initial penile scarring do not have a higher incidence of further scarring.

摘要

目的

我们试图确定使用前列腺素E1注射疗法的患者阴茎瘢痕形成的危险因素。

材料与方法

回顾了92例接受前列腺素E1治疗的患者的记录。采用统计学方法,对有瘢痕形成(15例)和无瘢痕形成(77例)的患者进行比较。

结果

两组在随访时间、注射频率、每次注射的前列腺素E1剂量、注射总数或前列腺素E1总剂量方面均未发现显著差异。初始阴茎有瘢痕形成的患者使用前列腺素E1后进一步形成瘢痕的发生率并未显著更高。

结论

前列腺素E1注射疗法导致的阴茎瘢痕形成是散发性的且不可预测。初始阴茎有瘢痕形成的患者进一步形成瘢痕的发生率并不更高。

相似文献

1
Penile scarring with intracavernous injection therapy using prostaglandin E1: a risk factor analysis.阴茎海绵体内注射前列腺素E1治疗所致阴茎瘢痕形成:危险因素分析
J Urol. 1996 Jan;155(1):138-40.
2
[Dose adaptation during training of intracavernous self-injections of prostaglandin E1].[前列腺素E1海绵体内自我注射训练期间的剂量调整]
Prog Urol. 1996 Aug-Sep;6(4):564-8.
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Nocturnal penile tumescence activity unchanged after long-term intracavernous injection therapy.长期海绵体内注射治疗后夜间阴茎勃起活动无变化。
J Urol. 2001 Mar;165(3):830-2; discussion 832-3.
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The long-term safety of alprostadil (prostaglandin-E1) in patients with erectile dysfunction. The European Alprostadil Study Group.前列地尔(前列腺素-E1)治疗勃起功能障碍患者的长期安全性。欧洲前列地尔研究小组。
Br J Urol. 1998 Oct;82(4):538-43.
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Quality of life in patients using self-administered intracavernous injections of prostaglandin E1 for erectile dysfunction.
J Urol. 1996 Jul;156(1):80-1.
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Papaverine-phentolamine and prostaglandin E1 versus papaverine-phentolamine alone for intracorporeal injection therapy: a clinical double-blind study.罂粟碱-酚妥拉明与前列腺素E1联合应用与单独应用罂粟碱-酚妥拉明用于体内注射治疗的临床双盲研究。
J Urol. 1995 Sep;154(3):1017-9.
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Prostaglandin E1 in the therapy of erectile deficiency.
Acta Eur Fertil. 1989 Sep-Oct;20(5):305-8.
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[Prostaglandin E1 in the diagnosis and therapy of erectile disorders].[前列腺素E1在勃起功能障碍的诊断与治疗中]
Urol Nefrol (Mosk). 1995 Jul-Aug(4):35-8.
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[Intracavernous injections of prostaglandin E1 in the treatment of erection disorders].
Arch Ital Urol Nefrol Androl. 1991 Dec;63(4):481-5.
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[Erectile response to intracavernous injection of linsidomine in 38 impotent patients. Comparison with prostaglandin E1].
Prog Urol. 1998 Jun;8(3):388-91.

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