罂粟碱-酚妥拉明与前列腺素E1联合应用与单独应用罂粟碱-酚妥拉明用于体内注射治疗的临床双盲研究。
Papaverine-phentolamine and prostaglandin E1 versus papaverine-phentolamine alone for intracorporeal injection therapy: a clinical double-blind study.
作者信息
Shenfeld O, Hanani J, Shalhav A, Vardi Y, Goldwasser B
机构信息
Chaim Sheba Medical Center, Tel Hashomer, Israel.
出版信息
J Urol. 1995 Sep;154(3):1017-9.
PURPOSE
A study was designed to compare intracorporeal injections of papaverine plus phentolamine (2-drug solution) and papaverine plus phentolamine and prostaglandin E1 (3-drug solution) for the treatment for impotence.
MATERIALS AND METHODS
A total of 20 impotent patients received intracorporeal injections of the 2-drug or 3-drug solution alternately during 2 sessions, and the quality and duration of erections were assessed.
RESULTS
Of the patients 73% achieved a full erection with the 3-drug solution compared to 28% with the 2-drug solution. The average duration of erections was 57 minutes and 33.6 minutes, respectively. The complication rate was similar for the 2 treatments.
CONCLUSIONS
Papaverine plus phentolamine and prostaglandin E1 is superior to papaverine plus phentolamine alone for the treatment of impotence.
目的
设计一项研究以比较阴茎海绵体内注射罂粟碱加酚妥拉明（二联溶液）和罂粟碱加酚妥拉明及前列腺素E1（三联溶液）治疗阳痿的效果。
材料与方法
总共20例阳痿患者在两个疗程中交替接受二联或三联溶液的阴茎海绵体内注射，并对勃起的质量和持续时间进行评估。
结果
73%的患者使用三联溶液后实现完全勃起，而使用二联溶液的患者这一比例为28%。勃起的平均持续时间分别为57分钟和33.6分钟。两种治疗的并发症发生率相似。
结论
罂粟碱加酚妥拉明及前列腺素E1治疗阳痿优于单独使用罂粟碱加酚妥拉明。
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