Rogowska-Szadkowska D, Borzuchowska A, Prokopowicz D, Chodynicka B, Rogowski F, Kramarz P
Klinika Obserwacyjno-Zakaźna.
Pol Arch Med Wewn. 1995 Jun;93(6):469-74.
The analyse of neopterin (NPT), beta 2-microglobulin (beta 2-M) and immunoglobulin A (IgA) in active and passive intravenous drug users was made to show the influence of intravenous drug taking on the level of so called "prognostic markers" in the serum of HIV infected persons. The intravenous drug users remained in the same, symptom-free stage of infection. The level of NPT in active drug users was higher than in passive drug users (statistically essential difference). In both analysed groups the level of NPT considerably exceeded the norm range (10 nmol/l). The differences in beta 2-M concentrations between analysed groups were not statistically essential, although higher values were observed in active drug users. The concentration of IgA in analysed persons were within the norm range. Current life conditions of the HIV-infected persons should be taken into consideration when estimating prognostic values of analysed indices.
对主动和被动静脉吸毒者的新蝶呤（NPT）、β2微球蛋白（β2-M）和免疫球蛋白A（IgA）进行分析，以显示静脉吸毒对HIV感染者血清中所谓“预后标志物”水平的影响。静脉吸毒者处于相同的无症状感染阶段。主动吸毒者的NPT水平高于被动吸毒者（有统计学显著差异）。在两个分析组中，NPT水平均大大超过正常范围（10 nmol/l）。分析组之间β2-M浓度的差异无统计学显著性，尽管主动吸毒者的值更高。分析对象的IgA浓度在正常范围内。在评估分析指标的预后价值时，应考虑HIV感染者当前的生活状况。
