Beckmann C, Reutter F, Gloor F
Schweiz Med Wochenschr. 1978 Dec 9;108(49):1991-3.
9 cases of "thorotrast kidney" after retrograde pyelography with reflux are presented. In 6 patients carcinoma of the renal pelvis developed 47--31 years after thorotrast pyelography. Because of this high rate of carcinoma induction, thorotrast kidney must be classified as a precancerous condition with high-rate tumor manifestation. Thorotrast kidney is diagnosed on X-ray by very opaque linear densities following the calices and pyelon. Early ureteronephrectomy is the treatment of choice in unilateral thorotrast kidneys. If uretero-nephrectomy is not possible, the patient should be followed up regularly with urinary cytologic examinations for early detection of malignancy.
本文报告了9例逆行肾盂造影伴反流后出现的“钍造影剂肾病”。6例患者在钍造影剂肾盂造影后47 - 31年发生肾盂癌。由于这种高致癌率，钍造影剂肾病必须被归类为具有高肿瘤发生率的癌前病变。钍造影剂肾病在X线片上表现为沿肾盏和肾盂走行的高密度线性影像。对于单侧钍造影剂肾病，早期输尿管肾切除术是首选治疗方法。如果无法进行输尿管肾切除术，则应对患者定期进行尿细胞学检查以早期发现恶性肿瘤。
