Ueda Y, Suenaga I
Animal Health Research Laboratories, Agro Division, Takeda Chemical Industries, Ltd., Kyoto, Japan.
J Vet Med Sci. 1995 Apr;57(2):363-4. doi: 10.1292/jvms.57.363.
A total of 90 strains of Actinobacillus pleuropneumoniae isolated from porcine pneumonic lungs in Japan during 1989 to 1993 were investigated for their in vitro susceptibility to florfenicol (a derivative of thiamphenicol) and other drugs. The minimal inhibitory concentrations of florfenicol against A. pleuropneumoniae ranged from 0.2 to 1.56 micrograms/ml with a peak at 0.39 microgram/ml. Florfenicol showed a high antibacterial activity against A. pleuropneumoniae regardless of the sensitivity of the strains to thiamphenicol.
对1989年至1993年期间从日本猪肺炎肺脏中分离出的90株胸膜肺炎放线杆菌进行了研究，以检测它们对氟苯尼考（甲砜霉素的衍生物）和其他药物的体外敏感性。氟苯尼考对胸膜肺炎放线杆菌的最低抑菌浓度范围为0.2至1.56微克/毫升，峰值为0.39微克/毫升。无论菌株对甲砜霉素的敏感性如何，氟苯尼考对胸膜肺炎放线杆菌均表现出高抗菌活性。
