McLaughlin S A, Ramsey D T, Lindley D M, Gilger B C, Gerding P A, Whitley R D
Department of Small Animal Surgery and Medicine, College of Veterinary Medicine, Auburn University, AL 36849-5523, USA.
J Am Vet Med Assoc. 1995 Dec 1;207(11):1441-3.
To determine the outcome of implantation of an intraocular silicone prosthesis (ISP) in the eyes of dogs and cats with intraocular neoplasia.
Retrospective case series.
Eight dogs and 1 cat with histologically confirmed intraocular neoplasia.
Signalment, clinical signs before and after surgery, results of microscopic examination of eviscerated intraocular tissues, follow-up information, and necropsy findings, if available, were recorded for each animal.
Five dogs and 1 cat had primary intraocular neoplasms. Two of the dogs developed regrowth of the neoplasm around the ISP 6 to 24 months after implantation, and the eyes were enucleated. The cat developed signs compatible with systemic metastasis 4 years after surgery and was euthanatized. Three dogs had multicentric or metastatic neoplasia involving the eye. Two of these dogs were euthanatized because of their systemic disease 1.5 to 7 months after ISP implantation. The third dog is alive without evidence of regrowth 3 years after surgery.
Intraocular neoplasia is not an absolute contraindication to ISP implantation.
确定在患有眼内肿瘤的犬猫眼中植入眼内硅胶假体（ISP）的结果。
回顾性病例系列。
8只犬和1只猫，组织学确诊为眼内肿瘤。
记录每只动物的特征、手术前后的临床症状、摘除的眼内组织的显微镜检查结果、随访信息以及尸检结果（如可获得）。
5只犬和1只猫患有原发性眼内肿瘤。其中2只犬在植入ISP后6至24个月，肿瘤在假体周围复发，随后摘除眼球。这只猫在手术后4年出现与全身转移相符的症状，随后实施安乐死。3只犬患有多中心性或转移性肿瘤累及眼部。其中2只犬在植入ISP后1.5至7个月因全身性疾病实施安乐死。第三只犬在手术后3年存活，无肿瘤复发迹象。
眼内肿瘤并非ISP植入的绝对禁忌证。
