Naranjo Carolina, Dubielzig Richard R
Departamento de Medicina y Cirugía Animales, Universidad Complutense de Madrid, Avda. Puerta de Hierro s/n, 28040, Madrid, Spain.
Vet Ophthalmol. 2014 Sep;17(5):343-50. doi: 10.1111/vop.12082. Epub 2013 Aug 1.
To characterize the histopathological causes for failure of intrascleral prosthesis placement in dogs and cats.
The Comparative Ocular Pathology Laboratory of Wisconsin database was searched to find canine and feline evisceration samples that were diagnosed with neoplasia. A second population included canine and feline scleral shells that were removed after an evisceration surgery had been performed. The causes for removal were divided into: neoplasia, corneal abnormalities, and other causes.
In dogs, 163 of 1985 evisceration samples (8.21%) contained a neoplasm, whereas 17 of 88 (19.31%) evisceration samples in cats contained a neoplasm. In dogs, severe corneal disease was diagnosed in 38 of 80 scleral shells (46.25%) and neoplasia was diagnosed in 31 of 80 scleral shells (38.75%). Malignant melanoma was the most frequently diagnosed tumor, in 14 of 31 scleral shells. In cats, eight of 12 scleral shells contained a tumor (66.7%), with feline diffuse iris melanoma being diagnosed most commonly (six of eight shells). Two of 12 feline scleral shells had severe corneal disease (16.7%). Epithelial downgrowth, lining the inner aspect of the fibrous tunic, was seen in 14 of 38 canine scleral shells and in two of two feline scleral shells with severe corneal disease.
Severe corneal disease and neoplasia are the most common causes for intrascleral prosthesis failure in dogs, whereas neoplasia is the single most common cause for intrascleral prosthesis failure in cats.
确定犬猫巩膜内植入物放置失败的组织病理学原因。
检索威斯康星比较眼病理学实验室数据库，以查找诊断为肿瘤的犬猫眼球摘除样本。第二个样本群体包括在眼球摘除手术后取出的犬猫巩膜壳。取出原因分为：肿瘤、角膜异常和其他原因。
在犬中，1985份眼球摘除样本中有163份（8.21%）含有肿瘤，而在猫中，88份眼球摘除样本中有17份（19.31%）含有肿瘤。在犬中，80个巩膜壳中有38个（46.25%）被诊断为严重角膜疾病，80个巩膜壳中有31个（38.75%）被诊断为肿瘤。恶性黑色素瘤是最常诊断出的肿瘤，在31个巩膜壳中有14个。在猫中，12个巩膜壳中有8个（66.7%）含有肿瘤，最常见的是猫弥漫性虹膜黑色素瘤（8个壳中有6个）。12个猫巩膜壳中有2个有严重角膜疾病（16.7%）。在38个犬巩膜壳中的14个以及2个患有严重角膜疾病的猫巩膜壳中的2个中，可见纤维膜内层的上皮内生。
严重角膜疾病和肿瘤是犬巩膜内植入物失败的最常见原因，而肿瘤是猫巩膜内植入物失败的唯一最常见原因。
