Sánchez Domínguez J
Sección de Cardiología, Hospital Virgen de la Salud, Toledo.
Rev Esp Cardiol. 1995;48 Suppl 4:49-56.
Among all the cardiovascular risk factors, Left Ventricular Hypertrophy (LVH) is the most important and its diagnosis by echocardiography is essential in routine evaluation of Arterial Hypertension (AHT). Calculation of the cardiac mass and of the relative thickness of the left ventricular wall are necessary steps in morphological classification of the heart of AHT into four subtypes: normal, concentric remodeling, concentric and eccentric hypertrophy. Study with M and 2D echo can be complemented by the analysis of systolic function and ventricular afterload. Alteration of the diastolic function by pulsed Doppler is sometimes the first sign of cardiac dysfunction in AHT. The three classic patterns of mitral filling, prolonged relaxation, restrictive and pseudonormal, often give only a rough analysis. The diversity of the factors involved in diastolic dysfunction opens the door to new indicators derived from analysis of flow in the pulmonary veins, especially the relative amplitude of the inverted "a" (ar) and "decalage" between this and the A of the anterograde mitral flow. The "decalage" between the inverted A (Ar) of the left ventricular outflow in relation to the mitral A is the latest approximation in the study of ventricular compliance. The poor overall prognosis which is implied by an increase in cardiac mass is modified by the geometric subtypes, the high morbidity and mortality of concentric hypertrophy being apparently noteworthy. The true prognostic significance of the regression of LVH and the accompanying diastolic dysfunction are still subject to debate.
在所有心血管危险因素中,左心室肥厚(LVH)最为重要,通过超声心动图对其进行诊断在动脉高血压(AHT)的常规评估中至关重要。计算心脏质量和左心室壁相对厚度是将AHT心脏形态学分为四种亚型的必要步骤:正常、向心性重构、向心性和离心性肥厚。M型和二维超声心动图研究可通过收缩功能和心室后负荷分析得到补充。脉冲多普勒检测到的舒张功能改变有时是AHT心脏功能障碍的首个迹象。二尖瓣充盈的三种经典模式,即舒张期延长、限制性和假性正常化,往往只能提供粗略的分析。舒张功能障碍涉及的因素多种多样,这为从肺静脉血流分析中得出的新指标打开了大门,尤其是反向“a”波(ar)的相对幅度以及它与二尖瓣前向血流A波之间的“时相延迟”。左心室流出道反向A波(Ar)与二尖瓣A波之间的“时相延迟”是心室顺应性研究中的最新近似指标。心脏质量增加所暗示的总体预后不良会因几何亚型而改变,向心性肥厚的高发病率和高死亡率显然值得关注。LVH消退及伴随的舒张功能障碍的真正预后意义仍存在争议。