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[大脑杏仁体:一些讨论话题及研究较少的问题]

[The amygdaloid body of the brain: some topics for discussion and little-studied problems].

作者信息

Akmaev I G, Kalimullina L B

出版信息

Usp Fiziol Nauk. 1995 Jan-Mar;26(1):3-24.

PMID:7495148
Abstract

Features of functional morphology of the amygdaloid brain complex (ABC) are analyzed in a new light presenting the notion of the ABC as a nucleo-paleocortical structure. The analysis of the structural organization of ABC could imply the presence of phylogenetically differentiated parts: the ancient, the old and the new amygdala. The presentation carries original data on the morphometric and histophysiological studies under various experimental alterations of the endocrine system. A concept is developed of the existence of a rostrocaudal gradient in the expression of sex-dependent structural and functional features of the amygdaloid complex as a neuroendocrine brain centre. Provided is technical recommendation for use in biological studies of amygdaloid brain complex mathematical models based on the theory of image identification. An original technique has also been recommended for selective dissection of the ABC with its eventual removal from nonfixed brain, which allows studies to be made of the ABC neurophysiological and neurochemical properties on surviving slices. Evidence is adduced indicating involvement of the ABC in the process of the brain sex differentiation.

摘要

从新的视角分析了杏仁核脑复合体(ABC)的功能形态特征,提出了ABC作为核-古皮质结构的概念。对ABC结构组织的分析可能意味着存在系统发育上分化的部分:古老杏仁核、旧杏仁核和新杏仁核。该报告提供了在内分泌系统各种实验改变下进行形态测量和组织生理研究的原始数据。提出了一个概念,即作为神经内分泌脑中心的杏仁核复合体的性别依赖性结构和功能特征的表达存在前后梯度。提供了基于图像识别理论用于杏仁核脑复合体数学模型生物学研究的技术建议。还推荐了一种原始技术,用于选择性解剖ABC并最终将其从未固定的大脑中取出,这使得能够在存活切片上研究ABC的神经生理和神经化学特性。有证据表明ABC参与了大脑性别分化过程。

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