Yabe Y, Muramatsu T, Nakano H, Wagatsuma K
Cardiovascular Diagnostic Laboratory Center, Toho University School of Medicine, Tokyo, Japan.
Angiology. 1995 Dec;46(12):1085-95. doi: 10.1177/000331979504601203.
The authors investigated the efficacy and prognosis of emergency percutaneous transluminal coronary angioplasty (PTCA) in elderly patients. A study was conducted on the early and late prognosis of the study group composed of 66 younger patients < sixty-five years in Group A and 46 elderly patients > or = seventy years in Group B who underwent reperfusion therapy, including PTCA, for acute myocardial infarction (AMI). No difference was seen in the initial success rate of 82% for Group A and 85% for Group B, or in the vessel patency in the predischarge coronary arteriogram (CAG) with 84% for Group A and 87% for Group B. However, in-hospital mortality was 3% for Group A and 11% for Group B. The patient restenosis rate in the 4.2 months follow-up CAG was 28% for Group A and 50% for Group B. The lesion restenosis rate was 30% for Group A and 53% for Group B (P < 0.05), and the late period mortality rate was 3% for Group A and 11% for Group B. Although there was no difference in the initial success rate of reperfusion through PTCA for AMI in the elderly as compared with the younger patient group, poorer results were seen in the restenosis rate and mortality rate.
作者研究了急诊经皮腔内冠状动脉成形术（PTCA）在老年患者中的疗效和预后。对A组66例年龄小于65岁的年轻患者和B组46例年龄大于或等于70岁的老年患者进行了一项研究，这些患者均接受了包括PTCA在内的急性心肌梗死（AMI）再灌注治疗。A组初始成功率为82%，B组为85%，出院前冠状动脉造影（CAG）显示血管通畅率A组为84%，B组为87%，两组之间未见差异。然而，A组住院死亡率为3%，B组为11%。在4.2个月随访CAG中，A组患者再狭窄率为28%，B组为50%。A组病变再狭窄率为30%，B组为53%（P<0.05），晚期死亡率A组为3%，B组为11%。尽管与年轻患者组相比，老年患者通过PTCA进行AMI再灌注的初始成功率没有差异，但在再狭窄率和死亡率方面结果较差。
