Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus.

The highlight of the past year was the demonstration that retrieval of endoplasmic reticulum membrane proteins containing the di-lysine motif involves COPI coat proteins. Other findings contributed to the debate about the nature of the 'intermediate compartment' between the endoplasmic reticulum and the Golgi apparatus, and the mechanism by which transported proteins are concentrated at this step.