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内质网与高尔基体之间的分选与回收

Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus.

作者信息

Pelham H R

机构信息

MRC Laboratory of Molecular Biology, Cambridge, UK.

出版信息

Curr Opin Cell Biol. 1995 Aug;7(4):530-5. doi: 10.1016/0955-0674(95)80010-7.

DOI:10.1016/0955-0674(95)80010-7
PMID:7495573
Abstract

The highlight of the past year was the demonstration that retrieval of endoplasmic reticulum membrane proteins containing the di-lysine motif involves COPI coat proteins. Other findings contributed to the debate about the nature of the 'intermediate compartment' between the endoplasmic reticulum and the Golgi apparatus, and the mechanism by which transported proteins are concentrated at this step.

摘要

过去一年的亮点是证明了含有双赖氨酸基序的内质网膜蛋白的回收涉及 COPI 衣被蛋白。其他发现引发了关于内质网和高尔基体之间“中间区室”的性质以及转运蛋白在此步骤中浓缩机制的争论。

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