血友病患者的抑制剂发展：理论背景与临床方面
Inhibitor development in haemophiliacs: theoretical background and clinical aspects.
作者信息
Sultan Y
机构信息
Centre de l'Accueil et de Traitement des Hemophiles, Hopital Chochin, Paris, France.
出版信息
Blood Coagul Fibrinolysis. 1995 Jul;6 Suppl 2:S55-7.
PMID:7495970
Abstract
The development of factor VIII inhibitors is one of the most serious complications of repeated transfusions in haemophilia patients, but it is not clear why the complication develops only in some haemophiliacs. This paper discusses the nature of FVIII inhibitors, their occurrence and detection, and outlines treatment procedures for haemophilia patients who show FVIII inhibitors.
摘要
凝血因子VIII抑制剂的产生是血友病患者反复输血最严重的并发症之一，但尚不清楚为何该并发症仅在部分血友病患者中出现。本文讨论了凝血因子VIII抑制剂的性质、其出现及检测情况，并概述了出现凝血因子VIII抑制剂的血友病患者的治疗程序。
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