Ohtani R, Hiasa Y
Second Department of Internal Medicine, School of Medicine, Tokushima University.
Intern Med. 1995 Jul;34(7):611-7. doi: 10.2169/internalmedicine.34.611.
Long-term follow-up of coronary artery stenosis was carried out in 81 patients undergoing successful percutaneous transluminal coronary angioplasty (PTCA). Progression of coronary stenosis was observed in 38 patients with 52 sites, and regression was seen in 23 patients with 23 sites during 2 years or more of follow-up. Progressive change occurred in three sites of 97 PTCA lesions and 49 of 1,090 non-PTCA lesions (no significant difference). On the other hand, regressive change was observed in 19 sites of PTCA lesions and four of non-PTCA lesions (p < 0.05). The percentage of narrowing in PTCA lesions was 28.0 +/- 14.4% at 3-6 months after PTCA, and this improved to 22.8 +/- 15.8% at late study angiography. Coronary score changes were -0.16 +/- 0.54 in PTCA lesions, and 0.08 +/- 0.46 in non-PTCA lesions (p < 0.01). We concluded that the progression of obstructive coronary artery disease in sites with previous PTCA is less than in those with non-PTCA.
对81例行成功的经皮腔内冠状动脉成形术（PTCA）的患者进行了冠状动脉狭窄的长期随访。在2年或更长时间的随访中，38例患者的52个部位观察到冠状动脉狭窄进展，23例患者的23个部位出现狭窄消退。97处PTCA病变中的3处和1090处非PTCA病变中的49处发生了进行性改变（无显著差异）。另一方面，在PTCA病变的19处和非PTCA病变的4处观察到了消退性改变（p<0.05）。PTCA术后3 - 6个月时，PTCA病变的狭窄百分比为28.0±14.4%，在后期研究血管造影时改善至22.8±15.8%。PTCA病变的冠状动脉评分变化为 - 0.16±0.54，非PTCA病变为0.08±0.46（p<0.01）。我们得出结论，既往行PTCA部位的阻塞性冠状动脉疾病进展小于未行PTCA的部位。
