de Goede E, Martens M, Van Rooy S, VanMoerkerke I
Salvator Hospital, Hasselt, Belgium.
Eur J Gastroenterol Hepatol. 1995 Aug;7(8):807-9.
An ex-coal miner was diagnosed with an idiopathic sigmoiditis compatible with colitis ulcerosa. He was treated with corticosteroids because of his deteriorating clinical condition, but his condition continued to worsen. He revealed to have a systemic Strongyloides stercoralis hyperinfection and Strongyloides colitis. A short time after diagnosis he died from septic shock despite therapy with thiabendazole and antibiotics. S. stercoralis is an opportunistic infection that is not uncommon and has high mortality in hyperinfection. It is prevalent in (sub)tropical areas, and also in coal mines because of the specific microclimate. However, the parasite is difficult to detect because eosinophilia can appear normal in chronic infection. Several stool examinations, duodenal aspiration or biopsies are necessary for a high diagnostic sensitivity. Serological diagnosis is the most sensitive and specific but is not always available.
一名前煤矿工人被诊断患有与溃疡性结肠炎相符的特发性乙状结肠炎。由于其临床状况不断恶化，他接受了皮质类固醇治疗，但病情仍继续恶化。他被发现患有全身性粪类圆线虫重度感染和类圆线虫结肠炎。诊断后不久，尽管接受了噻苯达唑和抗生素治疗，他仍死于感染性休克。粪类圆线虫是一种机会性感染，并不罕见，在重度感染中死亡率很高。它在（亚）热带地区很普遍，由于特定的微气候，在煤矿中也很常见。然而，这种寄生虫很难检测到，因为在慢性感染中嗜酸性粒细胞增多可能看起来正常。为了获得高诊断敏感性，需要进行多次粪便检查、十二指肠抽吸或活检。血清学诊断是最敏感和特异的，但并非总是可行。
