Szalaty H, Szulc B
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):503-8.
Production of interferon by the peritoneal and alveolar cells as well as the production of antibody-producing cells by spleen in the experimental influenza in the mouse has been studied. At the time when the replication of virus lung was at the peak the alveolar cells, but not peritoneal cells were found to produce in vitro more interferon than the cells from the uninfected mice. At the same time in the spleen increased number of antibody forming cells (PFC) against sheep red blood cells was observed. In contrast, after intravenous or intraperitoneal injection of 5 X 10(8) EID50 of influenza virus which induced approximately 10(3) units of interferon per ml there was an inhibition of PFC in the spleen.
已对小鼠实验性流感中腹膜细胞和肺泡细胞产生干扰素以及脾脏产生抗体生成细胞的情况进行了研究。在病毒在肺部复制达到高峰时，发现肺泡细胞而非腹膜细胞在体外产生的干扰素比未感染小鼠的细胞更多。与此同时，观察到脾脏中针对绵羊红细胞的抗体形成细胞（PFC）数量增加。相反，静脉内或腹腔内注射5×10⁸个EID₅₀流感病毒（每毫升诱导约10³个干扰素单位）后，脾脏中的PFC受到抑制。
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