Goad J R, Eastham J A, Fitzgerald K B, Kattan M W, Collini M P, Yawn D H, Scardino P T
Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA.
J Urol. 1995 Dec;154(6):2103-9. doi: 10.1016/s0022-5347(01)66706-5.
We determine whether autologous blood donation significantly decreases the need for homologous transfusions after radical prostatectomy.
The effects of estimated blood loss and autologous donation on the rate of homologous transfusions were analyzed in 3 groups of 100 consecutive patients treated between 1983 and 1992.
Overall, donors were less likely than nondonors to receive homologous blood. As median estimated blood loss decreased from 1,200 to 800 cc from groups 1 to 3 (p < 0.05), the incidence of nondonors requiring homologous blood decreased from 62 to 11% and that of autologous units transfused decreased from 96 to 19%.
With decreasing blood loss, safe but stringent criteria for transfusion and improved safety of the blood supply, autologous donation is an inefficient method to lower the slight risk of complications following homologous transfusion during radical prostatectomy.
我们确定自体献血是否能显著降低前列腺癌根治术后对异体输血的需求。
在1983年至1992年间连续治疗的3组每组100例患者中,分析估计失血量和自体献血对异体输血率的影响。
总体而言,献血者比非献血者接受异体血的可能性更小。随着第1组至第3组的中位估计失血量从1200 cc降至800 cc(p < 0.05),非献血者需要异体血的发生率从62%降至11%,输注的自体血单位发生率从96%降至19%。
随着失血量减少、安全但严格的输血标准以及血液供应安全性的提高,自体献血是一种低效的方法,无法降低前列腺癌根治术期间异体输血后轻微并发症的风险。