Grisold W, Drlicek M, Casati B, Setinek U, Wondrusch E
Neurologische Abteilung, Kaiser Franz Josef Spital, Wien.
Nervenarzt. 1995 Oct;66(10):736-44.
Paraneoplastic neurologic syndromes may be the presenting symptoms of cancer or appear during the course of the disease. Current knowledge of paraneoplastic syndromes is discussed on the basis of Henson and Urich's classification. The recognition of antineuronal antibodies in some neurologic paraneoplastic syndromes has had an impact on diagnostic possibilities. Additionally, there are new considerations relating to pathogenesis and therapy. Although the value and diagnostic yield of antineuronal antibodies are the subject of major discussion, they are already of significant diagnostic value in the diagnosis of paraneoplastic neurologic syndromes.
副肿瘤性神经系统综合征可能是癌症的首发症状，或在疾病过程中出现。本文基于亨森（Henson）和乌里奇（Urich）的分类法，对副肿瘤综合征的现有知识进行了讨论。在某些神经系统副肿瘤综合征中发现抗神经元抗体，对诊断可能性产生了影响。此外，在发病机制和治疗方面也有了新的思考。尽管抗神经元抗体的价值和诊断效能是主要讨论的话题，但它们在副肿瘤性神经系统综合征的诊断中已经具有重要的诊断价值。
