Ponte E, Cafagna D
Cattedra di Angiologia, Università degli Studi, Trieste.
Minerva Med. 1995 Sep;86(9):357-65.
Although the causes of high blood pressure vary, it is becoming clear that sustained hypertension is associated with changes in cardiovascular structure: left ventricular hypertrophy, decrease in big-medium arteries compliance and increased wall thickness of small arteries. To some extent, these alterations are natural physiological responses and are protective. However, the risk of circulatory death is closely related to left ventricular hypertrophy, and therefore, it is suggested increasingly that effective antihypertensive treatment requires normalization not only of blood pressure but also of vascular structure. The purpose of this brief review is to identify the type of functional and structural changes that are found in arteries of hypertensive individuals.
虽然高血压的病因各不相同,但越来越明显的是,持续性高血压与心血管结构的变化有关:左心室肥厚、大中动脉顺应性降低以及小动脉壁厚度增加。在某种程度上,这些改变是自然的生理反应,具有保护作用。然而,循环系统死亡风险与左心室肥厚密切相关,因此,越来越多的人认为有效的降压治疗不仅需要使血压正常化,还需要使血管结构正常化。这篇简短综述的目的是确定高血压患者动脉中发现的功能和结构变化类型。