Colivicchi F, Guerrera C, Bevilacqua E, Guerrera E, Melina D
Cattedra di Semeiotica e Metodologia Medica, Università Cattolica del Sacro Cuore, Roma.
Minerva Med. 1995 Sep;86(9):379-86.
Ischemic hepatitis represents a condition in which an acute circulatory failure determines a striking elevation of both serum transaminases and total bilirubin and a prolongation of prothrombin time. Such impairment of liver function tests is due to a haemodynamic hepatocyte injury, showing focal centrilobular necrosis as the specific pathologic correlate. In this paper the authors describe four different cases of ischemic hepatitis, in which an acute derangement of liver function tests occurred as a consequence either of myocardial failure or of systemic venous congestion. Finally, the authors review all current international literature concerning the various clinical, pathologic and therapeutic features of ischemic hepatitis.
缺血性肝炎是一种急性循环衰竭导致血清转氨酶和总胆红素显著升高以及凝血酶原时间延长的病症。肝功能检查的这种损害是由于血流动力学肝细胞损伤所致，表现为局灶性小叶中心坏死作为特定的病理关联。在本文中，作者描述了四例不同的缺血性肝炎病例，其中肝功能检查的急性紊乱是由心肌衰竭或全身静脉淤血引起的。最后，作者回顾了目前所有关于缺血性肝炎各种临床、病理和治疗特征的国际文献。
