Lynn S, Pool A, Rose D, Brey R, Suman V
Department of Otorhinolaryngolgy, Mayo Clinic, Rochester, MN 55905, USA.
Otolaryngol Head Neck Surg. 1995 Dec;113(6):712-20. doi: 10.1016/S0194-59989570010-2.
Thirty-six subjects with confirmed, unilateral benign paroxysmal positioning vertigo of at least 2 months' duration were randomly assigned to one of two treatment groups. After complete informational counseling and explanation of the posttreatment instructions, subjects were randomly assigned to receive either Epley's canalith repositioning procedure or a placebo maneuver. All subjects completed a daily diary for 1 month to document any dizzy spells and their adherence to the posttreatment instructions. Follow-up Dix-Hallpike testing was performed after 1 month by an audiologist who was blinded to the patient's treatment group status. Analysis of Dix-Hallpike results confirmed that those who received the canalith repositioning procedure had significantly more negative responses (88.9%) than did those in the placebo group (26.7%).
36名确诊为单侧良性阵发性位置性眩晕且病程至少2个月的受试者被随机分配到两个治疗组之一。在完成全面的信息咨询并解释治疗后的注意事项后,受试者被随机分配接受Epley半规管耳石复位法或安慰剂手法治疗。所有受试者连续1个月记录每日日记,以记录任何眩晕发作情况以及他们对治疗后注意事项的遵守情况。1个月后,由一名对患者治疗组情况不知情的听力学家进行随访Dix-Hallpike测试。对Dix-Hallpike测试结果的分析证实,接受半规管耳石复位法的受试者出现明显更多阴性反应(88.9%),高于安慰剂组(26.7%)。