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布鲁氏菌属、棘球绦虫属、盘尾丝虫属和血吸虫属物种之间密码子使用模式和偏好性的比较。

Comparison of the patterns of codon usage and bias between Brugia, Echinococcus, Onchocerca and Schistosoma species.

作者信息

Ellis J, Morrison D A, Kalinna B

机构信息

Faculty of Science, University of Technology Sydney, New South Wales, Australia.

出版信息

Parasitol Res. 1995;81(5):388-93. doi: 10.1007/BF00931499.

DOI:10.1007/BF00931499
PMID:7501637
Abstract

Patterns of codon usage and bias were compared among taxa of the genera Brugia, Echinococcus, Onchocerca and Schistosoma by metric multidimensional scaling and three commonly used indices of bias: Nc, GC3S and B. The overall codon usage for each taxon was compared, as was the codon usage for each individual gene within the taxa. Differences in the patterns of codon usage observed between taxa were dependent on the overall base composition of the genes analysed. The codon usage of Echinococcus was distinct from that of the other taxa. Furthermore, the pattern of codon usage detected by the average codon usage summed across all genes for each taxon was not shown by all genes from that taxon.

摘要

通过度量多维标度法以及三个常用的偏好指数

Nc、GC3S和B,比较了布鲁氏菌属、棘球绦虫属、盘尾丝虫属和血吸虫属各分类单元之间的密码子使用模式和偏好。比较了每个分类单元的总体密码子使用情况,以及各分类单元内每个单个基因的密码子使用情况。各分类单元之间观察到的密码子使用模式差异取决于所分析基因的总体碱基组成。棘球绦虫属的密码子使用情况与其他分类单元不同。此外,每个分类单元所有基因的平均密码子使用情况所检测到的密码子使用模式,并非该分类单元的所有基因都呈现。

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