Giovagnoni A, Valeri G, Ercolani P, Paci E, Carloni S, Soccetti A
Centro RM F. Angelini, Cattedra di Radiologia, Università degli Studi di Ancona.
Radiol Med. 1995 Sep;90(3):219-25.
The clinical usefulness of Magnetic Resonance Imaging (MRI) of the knee in the depiction of meniscal, ligament and tendon lesions is well known. In contrast, the role MRI plays in the diagnosis of chondromalacia remains debated, the gold standard being arthroscopy. A new technique, i.e., MR arthrography (MRA), has been recently proposed which consists of the intraarticular injection of a paramagnetic contrast agent (Gd-DTPA) during MRI. Thirty-one patients with clinically suspected chondromalacia of the knee were examined with MRA. The exams were performed with a 1T superconductive magnet and a dedicated coil. All the patients were examined before (baseline scans) and after paramagnetic contrast agent injection. MRA results were compared with arthrographic findings. Baseline MRI had 25% sensitivity, 77.9% specificity and 83% diagnostic confidence in the diagnosis of chondromalacia; these figures increased to 93%, 97.6% and 91.5% after contrast agent injection. This preliminary experience confirms MRA to be a useful tool in the diagnosis of chondral knee conditions.
磁共振成像（MRI）在显示膝关节半月板、韧带和肌腱损伤方面的临床实用性是众所周知的。相比之下，MRI在诊断软骨软化症中所起的作用仍存在争议，关节镜检查是金标准。最近提出了一种新技术，即磁共振关节造影（MRA），它包括在MRI期间关节内注射顺磁性造影剂（钆喷酸葡胺）。对31例临床怀疑膝关节软骨软化症的患者进行了MRA检查。检查使用1T超导磁体和专用线圈进行。所有患者在注射顺磁性造影剂之前（基线扫描）和之后均接受了检查。将MRA结果与关节造影结果进行了比较。基线MRI在诊断软骨软化症方面的敏感性为25%，特异性为77.9%，诊断可信度为83%；注射造影剂后，这些数字分别提高到93%、97.6%和91.5%。这一初步经验证实MRA是诊断膝关节软骨疾病的一种有用工具。
