大疱性表皮松解症的整形与重建手术：25例患者110例手术的临床经验

Plastic and reconstructive surgery in epidermolysis bullosa: clinical experience with 110 procedures in 25 patients.

作者信息

Ciccarelli A O, Rothaus K O, Carter D M, Lin A N

机构信息

Division of Plastic and Reconstructive Surgery, New York Hospital-Cornell Medical Center, New York, USA.

出版信息

Ann Plast Surg. 1995 Sep;35(3):254-61. doi: 10.1097/00000637-199509000-00006.

DOI:10.1097/00000637-199509000-00006

PMID:7503518

Abstract

We present clinical experience with 110 reconstructive procedures in 25 patients with epidermolysis bullosa, a group of rare heritable disorders characterized by marked fragility of the skin and mucosa. We discuss management of hand and foot deformities unique to epidermolysis bullosa patients, excision of squamous cell carcinoma, and reconstruction of oral, nasal, and ocular tissues. All patients underwent these procedures without major surgical or anesthetic complications. We analyze surgical outcome and formulate guidelines to avoid damaging the skin and mucosa.

摘要

我们介绍了对25例大疱性表皮松解症患者进行110次重建手术的临床经验，大疱性表皮松解症是一组罕见的遗传性疾病，其特征是皮肤和黏膜极度脆弱。我们讨论了大疱性表皮松解症患者特有的手足畸形的处理、鳞状细胞癌的切除以及口腔、鼻腔和眼部组织的重建。所有患者均接受了这些手术，未出现重大手术或麻醉并发症。我们分析了手术结果并制定了避免损伤皮肤和黏膜的指南。