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1
Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions.
Nucleic Acids Res. 1993 Dec 11;21(24):5656-60. doi: 10.1093/nar/21.24.5656.
2
Substitution of non-catalytic stem and loop regions of hammerhead ribozyme with DNA counterparts only increases KM without sacrificing the catalytic step (kcat): a way to improve substrate-specificity.
Nucleic Acids Symp Ser. 1992(27):17-8.
3
Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages.
Nucleic Acids Res. 1993 Jun 11;21(11):2605-11. doi: 10.1093/nar/21.11.2605.
4
Existence of efficient divalent metal ion-catalyzed and inefficient divalent metal ion-independent channels in reactions catalyzed by a hammerhead ribozyme.
Nucleic Acids Res. 2002 Jun 1;30(11):2374-82. doi: 10.1093/nar/30.11.2374.
5
Catalytic cleavage of cis- and trans-acting antigenomic delta ribozymes in the presence of various divalent metal ions.
Nucleic Acids Res. 2001 Nov 1;29(21):4482-92. doi: 10.1093/nar/29.21.4482.
6
A ribozyme with DNA in the hybridising arms displays enhanced cleavage ability.
Nucleic Acids Res. 1992 Nov 11;20(21):5737-41. doi: 10.1093/nar/20.21.5737.
7
Effects of deoxyribonucleotide substitutions in the substrate strand on hammerhead ribozyme-catalyzed reactions.
Gene. 1994 Nov 4;149(1):41-6. doi: 10.1016/0378-1119(94)90410-3.
8
Extraordinary enhancement of the cleavage activity of a DNA-armed hammerhead ribozyme at elevated concentrations of Mg2+ ions.
FEBS Lett. 1995 Jul 17;368(2):304-6. doi: 10.1016/0014-5793(95)00682-y.
9
Folding and activity of the hammerhead ribozyme.
Chembiochem. 2002 Aug 2;3(8):690-700. doi: 10.1002/1439-7633(20020802)3:8<690::AID-CBIC690>3.0.CO;2-C.
10
Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo.
Nucleic Acids Res. 1992 Sep 11;20(17):4559-65. doi: 10.1093/nar/20.17.4559.

引用本文的文献

1
Ribozyme Assays to Quantify the Capping Efficiency of In Vitro-Transcribed mRNA.
Pharmaceutics. 2022 Jan 29;14(2):328. doi: 10.3390/pharmaceutics14020328.
2
Measurements of weak interactions between truncated substrates and a hammerhead ribozyme by competitive kinetic analyses: implications for the design of new and efficient ribozymes with high sequence specificity.
Nucleic Acids Res. 2002 Jun 1;30(11):2383-9. doi: 10.1093/nar/30.11.2383.
3
Existence of efficient divalent metal ion-catalyzed and inefficient divalent metal ion-independent channels in reactions catalyzed by a hammerhead ribozyme.
Nucleic Acids Res. 2002 Jun 1;30(11):2374-82. doi: 10.1093/nar/30.11.2374.
4
In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme.
Nucleic Acids Res. 2000 Jan 15;28(2):481-8. doi: 10.1093/nar/28.2.481.
5
Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity.
Nucleic Acids Res. 1998 Jul 15;26(14):3385-91. doi: 10.1093/nar/26.14.3385.
6
A spermidine-induced conformational change of long-armed hammerhead ribozymes: ionic requirements for fast cleavage kinetics.
Nucleic Acids Res. 1997 Dec 1;25(23):4715-22. doi: 10.1093/nar/25.23.4715.
7
An ultraviolet crosslink in the hammerhead ribozyme dependent on 2-thiocytidine or 4-thiouridine substitution.
Nucleic Acids Res. 1997 Nov 1;25(21):4355-61. doi: 10.1093/nar/25.21.4355.
8
Use of intrinsic binding energy for catalysis by an RNA enzyme.
Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8497-502. doi: 10.1073/pnas.94.16.8497.
9
Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (p300) and luciferase.
Nucleic Acids Res. 1996 Aug 1;24(15):3010-6. doi: 10.1093/nar/24.15.3010.
10
Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes.
Nucleic Acids Res. 1996 Jun 15;24(12):2302-10. doi: 10.1093/nar/24.12.2302.

本文引用的文献

1
Theoretical analyses on the role of Mg2+ ions in ribozyme reactions.
FASEB J. 1993 Jan;7(1):137-42. doi: 10.1096/fasebj.7.1.8422960.
2
Metal ion catalysis in the Tetrahymena ribozyme reaction.
Nature. 1993 Jan 7;361(6407):85-8. doi: 10.1038/361085a0.
3
Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages.
Nucleic Acids Res. 1993 Jun 11;21(11):2605-11. doi: 10.1093/nar/21.11.2605.
4
A guide for probing native small nuclear RNA and ribonucleoprotein structures.
Methods Enzymol. 1989;180:212-27. doi: 10.1016/0076-6879(89)80103-x.
5
Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity.
Nature. 1990 Apr 5;344(6266):565-7. doi: 10.1038/344565a0.
6
Nuclear magnetic resonance studies of the hammerhead ribozyme domain. Secondary structure formation and magnesium ion dependence.
J Mol Biol. 1991 Jan 5;217(1):113-24. doi: 10.1016/0022-2836(91)90615-d.
7
Preferential chelation of cationic ligands to axial-equatorial oxygens over equatorial-equatorial dianionic oxygens: implication to the mechanism of action of ribozymes.
Nucleic Acids Symp Ser. 1991(25):107-8.
8
Role of divalent metal ions in the hammerhead RNA cleavage reaction.
Biochemistry. 1991 Oct 1;30(39):9464-9. doi: 10.1021/bi00103a011.
9
Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes.
Nucleic Acids Res. 1991 Mar 25;19(6):1183-8. doi: 10.1093/nar/19.6.1183.
10
Relationship between 2'-hydroxyls and magnesium binding in the hammerhead RNA domain: a model for ribozyme catalysis.
Biochemistry. 1991 Apr 23;30(16):4020-5. doi: 10.1021/bi00230a029.

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