胸腺微环境：生物活性不溶性组分的定位
The thymic microenvironment: localization of a biologically active insoluble fraction.
作者信息
Potworowski E F
出版信息
Clin Exp Immunol. 1977 Nov;30(2):305-8.
Abstract
An insoluble component of the thymus, previously shown to be capable of enhancing stem cell immigration into that organ, has been localized by immunofluorescence in perivascular basement membranes of the thymic medulla. It was found to be antigenically distinct from soluble thymic factor and from thymocyte membranes, and is thought to be responsible, in T-cell maturation, for the differentiation step preceding that imparted by thymic hormone.
摘要
胸腺的一种不溶性成分，先前已证明其能够增强干细胞向该器官的迁移，通过免疫荧光法已将其定位在胸腺髓质的血管周围基底膜中。发现它在抗原性上与可溶性胸腺因子和胸腺细胞膜不同，并且被认为在T细胞成熟过程中，负责胸腺激素作用之前的分化步骤。
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本文引用的文献
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Immunocompetence of embryonic hemopoietic cells after traffic to thymus.胚胎造血细胞迁移至胸腺后的免疫活性
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Studies on thymus products. II. Demonstration and characterization of a circulating thymic hormone.胸腺产物的研究。II. 一种循环胸腺激素的证明与特性分析。
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Specific antigenicity of thymic reticuloepithelial cells.
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[Role of an insoluble thymus fraction in the differentiation of T lymphocytes].[不溶性胸腺组分在T淋巴细胞分化中的作用]
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[The role of thymic microenvironment in T-cell maturation].
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Cellular localisation and antigenic species specificity of thymic factors.胸腺因子的细胞定位和抗原种类特异性
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