Jakóbiec T, Sedzimirska B, Zawisza T
Pol J Pharmacol Pharm. 1978 Sep-Oct;30(5):725-9.
Several new 4-substituted derivatives of hexahydrochromane were obtained. A new method for preparing the key intermediate for synthesis of this compounds i.e. ethyl 4-cyanohexahydrochromane-4-carboxylate 2 was elaborated. Comp. 8 shown central depressive activity.
得到了几种新的六氢色满4-取代衍生物。阐述了一种制备该化合物合成关键中间体即4-氰基六氢色满-4-羧酸乙酯2的新方法。化合物8显示出中枢抑制活性。
