Shulgovskiĭ V V, Latanov A V, Petrov G V
Vestn Ross Akad Med Nauk. 1994(1):49-52.
Behavioral changes and eye movements were studied through chronic low-dose MPTP exposure (ten intramuscular injections of 0.2 mg/kg per day) in four monkeys (Macaca rhesus). The monkeys developed the deficit of spontaneous saccades and decreased oculomotor range. The vertical component of saccades were hardly reduced. The examination of vestibuloocular reflex revealed no changes (r = approximately 1.0), but the fast phase of nystagmus was blocked.
通过对四只恒河猴进行慢性低剂量MPTP暴露(每天十次肌肉注射,每次0.2毫克/千克),研究行为变化和眼球运动。这些猴子出现了自发性扫视缺陷和动眼范围减小。扫视的垂直分量几乎没有减少。前庭眼反射检查未发现变化(r约为1.0),但眼球震颤的快相被阻断。