Did reflexive catalysts drive chemical evolution?

High-energy starting materials and energy sources on the primitive earth would have generated abundant and varied organic molecules of small or medium size. It is questionable, however, whether ordinary chemical evolution could have produced information-carrying polymers. The end point might have been a fixed steady state if some form of autocatalysis had not intervened. Autocatalytic synthesis is possible for small molecules as illustrated by the formose reaction, in which glycolaldehyde condenses with formaldehyde to form sugars, and resulting tetroses may cleave into two molecules of glycolaldehyde. This and other 'reflexive catalysts', some functioning in molecular aggregates, may have energized chemical evolution and carried it to a level at which RNA or an RNA analog could replicate itself.