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[尿路上皮肿瘤中的核仁组成区(Ag NORS)。附10例报告]

[The nucleolus organizer region (Ag NORS) in urothelial tumors. Apropos of 10 cases].

作者信息

Ben Rejeb A, Ben Moussa M

机构信息

Service d'Anatomie Pathologique, Hôpital Militaire, Tunis, Tunisie.

出版信息

Ann Urol (Paris). 1994;28(1):20-3.

PMID:7510464
Abstract

The authors study nucleolar organisers (Ag NORS) in ten cases of urothelial tumours, graded as grade I in five cases, grade II in two cases, grade III in two cases and intermediate grade II-III in one case. Study of the NOR index showed a mean value of 3.89 for grade I, 4.66 for grade II, 5.88 for grade III and 4.90 for the intermediate grade II-III. Different values were recorded in the same heterogeneous tumours containing tumour zones of different grades, providing an additional argument in favour of the heterogeneity of these urothelial tumours and accounting for the difficulties of their classification reported in the literature. Adequate sampling should allow a more objective and more representative study of all of the tumours examined.

摘要

作者研究了10例尿路上皮肿瘤中的核仁组织区(Ag NORS),其中5例为I级,2例为II级,2例为III级,1例为II-III级中间级。对核仁组织区指数的研究显示,I级的平均值为3.89,II级为4.66,III级为5.88,II-III级中间级为4.90。在含有不同分级肿瘤区域的同一异质性肿瘤中记录到了不同的值,这为这些尿路上皮肿瘤的异质性提供了额外的证据,并解释了文献中报道的其分类困难的原因。充分采样应能对所有检查的肿瘤进行更客观、更具代表性的研究。

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