Numerow L M, Kloiber R, Mitchell R J, Molnar C P, Anderson M A
Department of Radiological Sciences and Diagnostic Imaging, Foothills Hospital, Calgary, Alberta, Canada.
Clin Nucl Med. 1994 Jan;19(1):9-12. doi: 10.1097/00003072-199401000-00003.
Porous hydroxyapatite spheres are an ideal prosthetic device for orbital implantation because they are incorporated into soft tissues. Once vascularized, an eye prosthesis can be coupled to the sphere by a peg placed within a central motility hole. This hole should not be drilled while the sphere is avascular because of the risk of infection. Radionuclide scanning with Tc-99m methylene diphosphonate has been used to assess implant vascular ingrowth because radiophosphonate deposition within the sphere parallels vascularization. Using this technique, the authors examined the hydroxyapatite implants of 15 patients 6 months following insertion. Results showed that complete vascularization is best defined by planar imaging rather than SPECT. While the relative intensity of implant activity may be an important feature, uniformity of activity is probably more significant.
多孔羟基磷灰石球体是眼眶植入的理想假体装置，因为它们能融入软组织。一旦血管化，可通过置于中央活动孔内的栓子将眼假体与球体相连。由于存在感染风险，在球体无血管时不应钻孔。用锝-99m亚甲基二膦酸盐进行放射性核素扫描已被用于评估植入物的血管长入情况，因为球体内部放射性膦酸盐沉积与血管化情况平行。作者运用该技术，对15例患者植入羟基磷灰石6个月后的情况进行了检查。结果显示，平面显像比单光子发射计算机断层显像（SPECT）更能很好地界定完全血管化情况。虽然植入物活性的相对强度可能是一个重要特征，但活性的均匀性可能更具意义。
