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[对有多个性伴侣的异性恋者和性传播疾病患者中丙型肝炎病毒感染的调查]

[Investigations on hepatitis C virus infection among heterosexuals with multiple partners and patients with sexually transmitted diseases].

作者信息

Ding J

机构信息

Department of Infectious Diseases, Affiliated Hospital of Guiyang Medical College.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1993 Aug;14(4):231-3.

PMID:7511486
Abstract

The seroprevalence of antibody against hepatitis C virus (HCV) was assessed by an enzyme-linked immunosorbent assay (ELISA) in 110 heterosexually transmitted diseases (STDs), 98 heterosexuals with multiple partners, and 107 blood donors. The serum samples were also tested for hepatitis B virus surface antigen (HBsAg) and antibody against hepatitis B core antigen (anti-HBc). Of the patients with STDs 12.7% (13/110) were anti-HCV antibody positive; of heterosexuals with multiple sexual partners, 4.1% (4/98) positive; of blood donors, 1.87% (2/107) positive. Among the 18 cases of HCV infection, 3 were positive for HBsAg and 10 were positive for anti-HBc antibody. There was no relationship among HCV infection, sex and age in observed objects. From the present data, we can conclude that HCV infection should not be ignored in heterosexuals with multiple partners and patients with STDs, and the risk factor for HCV infection appeared to be associated with a history of STDs and with HBV infection.

摘要

通过酶联免疫吸附测定(ELISA)对110例异性传播疾病(STD)患者、98例有多个性伴侣的异性恋者以及107名献血者进行了丙型肝炎病毒(HCV)抗体血清流行率评估。血清样本还检测了乙型肝炎病毒表面抗原(HBsAg)和乙型肝炎核心抗原抗体(抗-HBc)。STD患者中12.7%(13/110)抗-HCV抗体呈阳性;有多个性伴侣的异性恋者中,4.1%(4/98)呈阳性;献血者中,1.87%(2/107)呈阳性。在18例HCV感染病例中,3例HBsAg呈阳性,10例抗-HBc抗体呈阳性。观察对象中HCV感染与性别和年龄之间无关联。根据目前的数据,我们可以得出结论,有多个性伴侣 的异性恋者和STD患者中的HCV感染不容忽视,HCV感染的危险因素似乎与STD病史和HBV感染有关。

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