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Antimutagenicity in Euglena gracilis.

作者信息

Foltínová P, Lahitová N, Ebringer L

机构信息

Institute of Molecular and Subcellular Biology, Comenius University, Bratislava, Slovak Republic.

出版信息

Mutat Res. 1994 Apr;323(4):167-71. doi: 10.1016/0165-7992(94)90029-9.

DOI:10.1016/0165-7992(94)90029-9
PMID:7512686
Abstract

The genotoxic effect of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and furadantine (Fu) was significantly decreased by standard antimutagens (ascorbic acid, alpha-tocopherol, chlorophyllin and sodium selenite) in the unicellular flagellate Euglena gracilis. The effects of these compounds were verified also by a bacterial test in which three strains of Salmonella typhimurium, TA97, TA100, and TA102, were used. The above compounds were antimutagenic in strains of bacteria used, except for chlorophyllin which had no effect on strain TA102.

摘要

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