Shadduck J A, Reedy L, Lawton G, Freeman R
Vet Pathol. 1978 Nov;15(6):716-24. doi: 10.1177/030098587801500603.
A dog with a lymphoproliferative disease resembling mycosis fungoides in man, the second reported canine case, had slowly progressive, multicentric cutaneous nodules and plaques. Nearly half the body surface was involved. The lesions consisted of multiple, flat, infiltrative, cutaneous tumors composed of heterogeneous, pleomorphic cells, some of which resembled histiocytes or activated lymphocytes. Intracutaneous foci of tumor cells and numerous tumor cells with bizarre convoluted nuclei were distinctive features that permitted the lesions to be distinguished from other non-epithelial cutaneous neoplasms.
一只患有类似于人类蕈样肉芽肿的淋巴增生性疾病的狗，这是第二例报告的犬类病例，有缓慢进展的多中心性皮肤结节和斑块。近一半的体表受累。病变由多个扁平、浸润性皮肤肿瘤组成，肿瘤细胞异质、多形，其中一些类似于组织细胞或活化淋巴细胞。肿瘤细胞的皮内灶和许多具有奇异扭曲核的肿瘤细胞是其独特特征，使得这些病变能够与其他非上皮性皮肤肿瘤区分开来。
