McKeever P J, Grindem C B, Stevens J B, Osborne C A
J Am Vet Med Assoc. 1982 Mar 1;180(5):531-6.
Cutaneous lymphoma (mycosis fungoides) was diagnosed by multiple biopsies of nonulcerated cutaneous lesions in 13 dogs. The disease was initially characterized by erythema and alopecia of the trunk. Subsequently severe scaling, pruritus, and skin nodules developed. Lymph nodes were usually normal in size during early stages of the disease but became enlarged as the disease became extensive. Four dogs were treated with cytotoxic drugs. Marked improvement of skin lesions occurred in 3 dogs, but treatment did not prevent development of extra-cutaneous lesions.
通过对13只犬的非溃疡性皮肤病变进行多次活检,诊断出皮肤淋巴瘤(蕈样霉菌病)。该病最初表现为躯干红斑和脱毛。随后出现严重脱屑、瘙痒和皮肤结节。在疾病早期,淋巴结大小通常正常,但随着疾病进展会肿大。4只犬接受了细胞毒性药物治疗。3只犬的皮肤病变有明显改善,但治疗未能阻止皮肤外病变的发展。