Nakanishi R, Shirakusa T, Takachi T
Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Ann Thorac Surg. 1994 Apr;57(4):841-5. doi: 10.1016/0003-4975(94)90186-4.
An effective method of vascularization is required in tracheal transplantation, as tracheal vessels are too find to be anastomosed easily. A series of experiments, including postmortem injection study, were conducted to assess the usefulness of omentopexy for tracheal autografts in 17 dogs. In group I (n = 4) a six-ring tracheal autograft was implanted in the greater omentum for 28 days. The structural integrity of all the autografts was maintained. In group II (n = 3) a six-ring cervical trachea was excised and reimplanted as an autograft without omental wrapping. All three autografts dissolved or transformed. No neovascularity from the recipient trachea or surrounding tissue was seen in the autografts by postoperative day 11. In group III (n = 10) omentopexy was added to the same experiment as group II. All the autografts were nourished adequately by the omental circulation as demonstrated by injection study, and remained viable early after transplantation. We conclude that the omentopexy is an effective method to facilitate neovascularization in tracheal autografts.
气管移植需要一种有效的血管化方法，因为气管血管太细，难以轻易进行吻合。进行了一系列实验，包括尸检注射研究，以评估网膜固定术对17只狗气管自体移植的有效性。在第一组（n = 4）中，将一个六环气管自体移植物植入大网膜中28天。所有自体移植物的结构完整性得以维持。在第二组（n = 3）中，切除一个六环颈段气管并作为自体移植物重新植入，未进行网膜包裹。所有三个自体移植物均溶解或变形。术后第11天，在自体移植物中未观察到来自受体气管或周围组织的新生血管。在第三组（n = 10）中，在与第二组相同的实验中增加了网膜固定术。注射研究表明，所有自体移植物均由网膜循环充分滋养，并在移植后早期保持存活。我们得出结论，网膜固定术是促进气管自体移植物新生血管化的有效方法。
