[Ventricular arrhythmia during cesarean section due to intramyometrically administered prostaglandin F2 alpha: report of two cases].

Case 1 was a healthy 28 year old woman. Spinal anesthesia was performed for Cesarean section. After the delivery, prostaglandin F2 alpha (PGF2 alpha) 1000 micrograms was administered intramyometrically. Immediately ventricular premature beats appeared on ECG and heart rate decreased to 60.min-1. Atropine sulfate 0.25 mg was administered and ECG showed sinus tachycardia. Case 2 was a 28 year old healthy woman. Spinal anesthesia was induced for Cesarean section. PGF2 alpha 1000 micrograms was injected to the myometrium. Soon thereafter blood pressure rose to 170/105 mmHg and ECG showed multifocal ventricular premature beats. Lidocaine 40 mg and nicardipine hydrochloride 0.4 mg were administered. Blood pressure decreased to 120/80 mmHg and ECG showed sinus tachycardia. These cases demonstrate the systemic reaction of intramyometrically administered PGF2 alpha.